Tumor necrosis factor receptor associated factor 6 (TRAF6)

Details Tumor necrosis factor receptor associated factor 6 (TRAF6) Tumor necrosis factor receptor associated factor 6 (TRAF6)

1996-04-19

1998-01-20

Chambers, Jasemine C.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving viable micro-organism

435 6, 435 4, 435 691, 536 231, 536 235, 536 243, 536 2431, 536 2433, C12Q 102, C12Q 168, C07H 2100, C12N 1512

Patent

active

057100136

ABSTRACT:
The invention provides methods and compositions relating to a novel tumor necrosis factor receptor associated factor number six (TRAF6) protein, which transcriptionally activates Nuclear Factor .kappa.B. The invention provides isolated TRAF6 hybridization probes and primers capable of hybridizing with the disclosed TRAF6 gene, nucleic acids encoding the subject TRAF6 proteins, methods of making the subject TRAF6 proteins, and methods of using the subject compositions in diagnosis and drug screening.

REFERENCES:
Ngo et al., The Protein Folding Problem and Tertiary Structure Prediction, Mertz et al. (ed.) Birkhauser, Boston, MA, p. 433 and 492-495, 1994.
Hillier et al., "yd38c04.s1 Homo sapiens cDNA clone 110502 3'", EST-STS TWO accession T89991, Mar. 20, 1995.
Hillier et al., "yd38c04.r1 Home sapiens cDNA clone 110502 5'", EST-STS TWO accession T82812, Mar. 16, 1995.
Rothe et al., "TRAF2-mediated activation of NF-kappaB by TNF receptor 2 and CD40", Science 269:1424-1427, Sep. 1995.
Fields et al., "The two-hybrid system: an assay for protein-protein interactions", Trends Genet. 10:286-292, Aug. 1994.

Affiliated with

Also associated with

Rating

Tumor necrosis factor receptor associated factor 6 (TRAF6) does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Tumor necrosis factor receptor associated factor 6 (TRAF6), we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tumor necrosis factor receptor associated factor 6 (TRAF6) will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-724520