Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.
Patent
1995-10-04
1998-06-30
Draper, Garnette D.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Lymphokines, e.g., interferons, interlukins, etc.
424 851, 514 2, 514 8, 514 12, 930140, C07K 1452, A61K 3819
Patent
active
057735824
ABSTRACT:
Muteins of human tumor necrosis factor (hTNF), a process for production thereof, and DNAs encoding these muteins are found to have a superior antitumor activity and lower acute lethal toxicity compared to the wild-type human tumor necrosis factor.
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Kang Sungzong
Lee Inkyung
Shin Hang-Cheol
Shin Nam-Kyu
Draper Garnette D.
Hanil Synthetic Fiber Co., Ltd.
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