Tumor necrosis factor formulations

Details Tumor necrosis factor formulations Tumor necrosis factor formulations

1988-04-13

1993-06-01

Stone, Jacqueline

Drug, bio-affecting and body treating compositions

Lymphokine

514 8, 514 21, 514777, 514970, A61K 4505, A61K 3702

Patent

active

052157431

ABSTRACT:
Compositions are described that are suitable for formulating cytokines, preferably tumor necrosis factor, that maintain their biological activities over a wide range of temperatures by, among other aspects, decreasing them sensitivity to agitation, and preventing oligomer and particulate matter formation.

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patent: 4677063 (1987-06-01), Mark et al.
patent: 4677064 (1987-06-01), Mark et al.
patent: 4762857 (1988-08-01), Bollin, Jr. et al.
patent: 4797388 (1989-01-01), Francis
patent: 4810827 (1989-03-01), Mitsuhashi et al.

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