Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure
Patent
1980-03-03
1982-05-25
Nucker, Christine M.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
Molecular bilayer structure
424 9, A61K 4900, A61K 4300
Patent
active
043316476
ABSTRACT:
Methods are provided for using radiolabeled antibody fragments specific to tumor-associated markers for detection, localization and therapy of tumors. Mixtures of labeled fragments with varied specificity or multivalent hybrid fragments permit detection and localization of more than one tumor or tumor cell type. Antibodies and injectable compositions for use in the methods of the invention are also provided.
REFERENCES:
patent: 3927193 (1975-12-01), Hansen
patent: 4036945 (1977-07-01), Haber
patent: 4146603 (1979-03-01), Davidson et al.
patent: 4234561 (1980-11-01), Bahl
Quinones et al., J. Nucl. Med., vol. 12, 1971, pp. 69-75.
Hawthorne et al., J. Med. Chem., 15, 449 (1972).
Order, Radiology, 118, 219 (1976).
Ettinger et al., Cancer Treat. Rep., 63, 131 (1979).
Order et al., Int. J. Radiation Oncology Biol. Phys., 6, 703 (1980).
Goldenberg et al., N. Eng. J. Med., 298, 1384 (1978).
Lee et al., Cancer Chemother. Pharmacol., 3, 17 (1979).
Nisonoff et al., Arch. Biochem. Biophys., 89, 230 (1960).
Nisonoff et al., Arch. Biochem. Biophys., 93, 460 (1961).
Nisonoff et al., Nature, 189, 293 (1961).
Porter, Biochem. J., 73, 119 (1959).
Cebra et al., J. Biol. Chem., 236, 1720 (1961).
Hammerling et al., J. Exp. Med., 128, 1461 (1968).
Bale et al., Cancer Res., 40, 2965 (1980).
Koji et al., Cancer Res., 40, 3013 (1980).
Order et al., Cancer Res., 40, 3001 (1980).
LandOfFree
Tumor localization and therapy with labeled antibody fragments s does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Tumor localization and therapy with labeled antibody fragments s, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tumor localization and therapy with labeled antibody fragments s will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2076600