Tumor-associated antigen, antibodies, compositions and uses ther

Details Tumor-associated antigen, antibodies, compositions and uses ther Tumor-associated antigen, antibodies, compositions and uses ther

1992-08-31

1993-10-05

Wax, Robert A.

Drug, bio-affecting and body treating compositions

Lymphokine

530350, 530395, 5303888, 530403, A61K 3900, C07K 1500

Patent

active

052502970

ABSTRACT:
A novel tumor-associated antigen expressed by lung adenocarcinoma is disclosed. The antigen, characterized by monoclonal antibody LA20207, has a molecular weight in the range of about 50,000 to about 80,000 daltons and an isoelectric point in the range of about 4.9 to about 6.5. Antibodies directed against the antigen, methods for their production and diagnostic and therapeutic uses therefor are also provided.

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