Tumor antigens and uses thereof

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...

Reexamination Certificate

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C435S320100, C536S023100, C536S024300, C530S350000

Reexamination Certificate

active

09762577

ABSTRACT:
The invention features tumor antigens; tumor antigen-encoding nucleic acids; antibodies specific for tumor antigens and methods of using the antibodies; methods of identifying tumor antigens and the nucleic acids that encode them; methods of monitoring or diagnosing tumors in patients; methods of testing patients for the increased likelihood of developing a tumor; and methods and compositions for treatment of a tumor or prophylaxis against developing a tumor.

REFERENCES:
patent: 5840708 (1998-11-01), Weiss
patent: 6472172 (2002-10-01), Deng et al.
Bowie et al (Science, 1990, 257:1306-1310).
Burgess et al (J of Cell Bio. 111:2129-2138, 1990).
Lazar et al (Molecular and Cellular Biology, 1988, 8:1247-1252).
Miller (1995, FASEB J., vol. 9, pp. 190-199).
Deonarain (1998, Expert Opin. Ther. Pat., vol. 8, pp. 53-69).
Verma (Sep. 1997, Nature, vol. 389, pp. 239-242).
Crystal (1995, Science, vol. 270, pp. 404-410).
Branch, AD, 1998, TIBS 23: 45-50.
Gura (Science, 1995, 270:575-577).
MPSRCH search report, 2006, us09-762-577b-11.rni, pp. 2-3; and.
MPSRCH search report, 2006, us-09-762-577b-12.p2n.rni, pp. 2-3.
White et al, 2001 (Ann Rev Med, 52: 125-145).
Boon, 1992 (Adv Can Res, 58:177-210).
Ezzell, 1995 (J. NIH Res, 7:46-49).
Spitler, 1995 (Cancer Biotherapy, 10:1-3).
Gura, 1997, (Science, 278:1041-1042).
Jain, 1994 (Sci. Am., 271:58-65).
Curti, 1993 (Crit. Rev. in Oncology/Hermatology, 14:29-39).
Hartwell et al (Science, 1997, 278:1064-1068).
Dranoff et al., “Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity,” Proc. Natl. Acad. Sci. U.S.A. 90:3539-3543, 1993.
Dranoff et al., “A phase I study of vaccination with autologous, irradiated melanoma cells engineered to secrete human granulocyte-macrophage colony stimulating factor,” Human Gene Therapy 7:111-123, 1997.
Ellem et al., “A case report: Immune responses and clinical course of the first human use of granulocyte/macrophage-colony-stimulating-factor-transduced autologous melanoma cells for immunotherapy,” Cancer Immunol. Immunother. 44:10-20, 1997.
Jäger et al., “Strategies for the development of vaccines to treat breast cancer,” Recent Results Cancer Res. (Germany) 152:94-102, 1998.
Scanlan et al., “Characterization of human colon cancer antigens recognized by autologous antibodies,” Int. J. Cancer 76:652-658, 1998.
Simons et al., “Bioactivity of autologous irradiated renal cell carcinoma vaccines generated by ex vivo granulocyte-macrophage colony-stimulating factor gene transfer,” Cancer Research 57:1537-1546, 1997.
Soffer et al., “Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte-macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma,” Proc. Natl. Acad. Sci. U.S.A. 95:13141-13146, 1998.
Takahashi et al., “707-AP peptide recognized by human antibody induces human leukocyte antigen A2-restricted cytotoxic T lymphocyte killing of melanoma,” Clin. Cancer Res. 3:1363-1370, 1997.
Genbank Accession No. AI459806, Hillier et al., WashU-NCI human EST Project, Mar. 9, 1999.
Genbank Accession No. AI590782, NCI-CGAP http://www.ncbi.nih.gov
cicgap, National Cancer Institute, Cancer Genoma Anatomy Project (CGAP), Tumor Gene Index, May 14, 1999.
Genbank Accession No. AI115047, Marra et al., The WashU-HHMI Mouse EST Project, Sep. 2, 1998.

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