Tuftsin metallopeptide analogs and uses thereof

Details Tuftsin metallopeptide analogs and uses thereof Tuftsin metallopeptide analogs and uses thereof

2006-08-29

2006-08-29

Jones, Dameron L. (Department: 1618)

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

In an organic compound

C424S001110, C424S001650, C424S009100, C530S330000

Reexamination Certificate

active

07097824

ABSTRACT:
Tuftsin receptor-specific peptides, peptidomimetics and peptide-like constructs are provided, particularly for use in biological, pharmaceutical and radiopharmaceutical applications, in which the peptide, peptidomimetic or construct is conformationally fixed on complexation of the metal ion-binding portion thereof with a metal ion, resulting in a peptide, peptidomimetic or construct with increased affinity for the tuftsin receptor.

REFERENCES:
patent: 5443816 (1995-08-01), Zamora et al.
patent: 5569745 (1996-10-01), Goodbody et al.
patent: 5891418 (1999-04-01), Sharma
patent: 6027711 (2000-02-01), Sharma
patent: 6551574 (2003-04-01), Sharma
patent: 2003/0165427 (2003-09-01), Sharma
Som et al., “Diagnosis of Osteomyelitis and Soft Tissue Infection Using a TC-99m Labeled Tuftsin-Analog Peptide”,The Journal of Nuclear Medicine, vol. 38: 132P, No. 493.

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