Chemistry: physical processes
Patent
1977-10-31
1980-09-09
Krizmanich, George H.
Chemistry: physical processes
233 1R, B04B 908
Patent
active
042213223
ABSTRACT:
A 2:1 compensating rotor is used in a continuous-flow centrifuge system, thereby allowing the dynamic loading and unloading of biological suspensions and processing solutions in a "closed" fashion without resort to rotary seals. Improved performance is obtained by relieving the mechanical stresses associated with the 2:1 relative motion between rotary components. In zones of high flexural and torsional stress low-friction bearing mounted tube constraint fittings are utilized to minimize tubing loop wear and risk of rupture. Similarly, in regions of high centrifugal force a tube guide insert is utilized to separate and constrain the discrete fluid-carrying tubes, thereby minimizing abrasion induced by the relative motion between the discrete tubes, as well as minimizing abrasion induced by the relative motion between the discrete tubes and the inner walls of the tube guide assembly.
REFERENCES:
patent: 2135835 (1938-11-01), Papello
patent: 2666188 (1954-01-01), Klein
patent: 3347454 (1967-10-01), Bellamy et al.
patent: 3358072 (1967-12-01), Wrench
patent: 3986442 (1976-10-01), Khoja et al.
patent: 4056224 (1977-11-01), Lola chi
Drago James A.
Savitz Steven R.
Krizmanich George H.
McCarthy, Jr. Frederick J.
Union Carbide Corporation
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