Trypanosoma cruzi glycoprotein vaccine for inducing immunity to

Details Trypanosoma cruzi glycoprotein vaccine for inducing immunity to Trypanosoma cruzi glycoprotein vaccine for inducing immunity to

1980-03-26

1981-11-03

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Lymphokine

A61K 39005

Patent

active

042985960

ABSTRACT:
A novel, glycoprotein antigen obtained from T. cruzi organisms can be used in vaccines for inducing immunity in humans to Chagas' disease. The glycoprotein is extracted by treating trypanosomes with a detergent and separating it from the cell debris and other proteinaceous material by affinity chromatography using lectin with affinity for glucose, mannose or galactose.

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