Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.
Patent
1986-09-04
1991-05-21
Teskin, Robin L.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Lymphokines, e.g., interferons, interlukins, etc.
435 6952, 435 91, 4351723, 43525233, 536 27, 935 19, 935 29, 935 41, 935 56, 935 61, 935 73, 935 81, C07K 1300, C12P 2106, C12P 1934, C12N 1500, C12N 122, C07H 1512
Patent
active
050176927
ABSTRACT:
Synthetic human interleukin-1.alpha. genes are provided whose codons are selected from those preferred by bacteria. High expression levels are obtained in an E. coli expression system for both native interleukin-1.alpha. and several mutant interleukin-1.alpha.'s.
REFERENCES:
patent: 4571421 (1986-02-01), Itakura
patent: 4695623 (1987-09-01), Stabinsky
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Zurawski Gerard
Zurawski Sandra M.
Ellis Joan
Macevicz Stephen C.
Schering Corporation
Teskin Robin L.
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