Troxerutin with a high content of trihydroxyethylrutoside...

Details Troxerutin with a high content of trihydroxyethylrutoside... Troxerutin with a high content of trihydroxyethylrutoside...

2005-02-15

2005-02-15

Barts, Samuel (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S027000, C514S025000, C536S004100

Reexamination Certificate

active

06855697

ABSTRACT:
The invention concerns novel troxerutin with high trihydroxy-ethyl-rutin content. Said troxerutin has at least 92 wt. % of 7,3′,4′-trihydroxyethyl rutin and a wettability expressed in minutes less than 10 minutes, when said wettability is measured in a test consisting in measuring the time taken by 3.5 g of said enriched troxerutin powder to leave the surface of a beaker containing 100 ml of water, at a stabilised temperature of 20° C., when said enriched troxerutin powder is poured at the surface of the water in said beaker, and a wettability less than 100 seconds when said wettability is measured in a test consisting in measuring the time taken by said enriched troxerutin to be wetted by the water contained in a receptacle, such as a beaker, when said enriched troxerutin has been deposited at the surface of the water, in the form of cores of 2 mm wide and 3 mm high weighing 63 ? 2 mg, at a stabilised temperature of 20° C. Said troxerutin has improved properties of wettability and solubility in water.

REFERENCES:
patent: 3420815 (1969-01-01), Courbat
patent: 2 267 327 (1975-11-01), None
patent: 1 497 157 (1978-01-01), None
H. Cai et al., “Purification of (hydroxyethyl)rutin Derivatives”, Chemical Abstracts, vol. 113, No. 17, pp. 832 (Oct. 22, 1990).

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