Tropolone derivatives and pharmaceutical composition thereof for

Details Tropolone derivatives and pharmaceutical composition thereof for Tropolone derivatives and pharmaceutical composition thereof for

1995-05-18

1997-01-14

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548180, 546199, 544135, 544369, C07D27766, C07D40110, A61K 31425, A61K 31445

Patent

active

055941443

ABSTRACT:
The present invention provides novel tropolone derivatives of the formula I ##STR1## wherein R.sub.10 is a substituted or unsubstituted piperazinyl or benzothiazolidinyl group, and pharamaceutical compositions thereof. These compounds are useful for the prevention and treatment of ischemic diseases, including cerebrovascular diseases and cardiovascular diseases.

REFERENCES:
Chemical Abstracts, vol. 79, No. 11, 17 Sep. 1973, Hikaru Ozawa, #61705m 1973.
Chemical Abstracts, vol. 77, No. 15, 9 Oct. 1972, Hikaru Ozawa, #96876d 1972.
Chemical Abstracts, vol. 76, No. 25, 19 Jun. 1972, Hikaru Ozawa, #149003e 1972.
Banner, Perspect. Mach. Chem., pp. 27-43, 1993 1993.
Shuman, J. Med. Chem., vol. 36, pp. 314-319, 1993 1993.

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