Tropinin I calibrator and method of use thereof in a sandwich im

Details Tropinin I calibrator and method of use thereof in a sandwich im Tropinin I calibrator and method of use thereof in a sandwich im

1996-12-13

1999-07-20

Spiegel, Carol A.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 71, 435967, 435972, 436518, 436 8, 436 15, 436811, 436815, 5303911, 5303915, 5303917, 5303919, 530807, G01N 3353

Patent

active

059255331

ABSTRACT:
A conjugate consisting of a sequence of the analyte and an antibody against one of the antibodies used in the test can be employed, in aqueous solution and in precisely known quantity, as a stable calibrator in a sandwich immunoassay for detecting the analyte.

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S. Yoshitake et al, Eur.J. Biochem., 101:395, 1979.
W.J. Vallins et al, Molecular Cloning of Human Cardiac Troponin I Using Polymerase Chain Reaction, FEBS 270:37-61, 1990.
Biosis No. 73032155 abstract of Oeltmann et al., "Inhibition of Mouse Spleen Cell Function by Diptheria Toxin Fragment A Coupled to Anti-Mouse THY-1.2 and by Ricin A Chain Coupled to Antimouse Immunoglobulin M," Arch. Biochem. Biophys, 209(2):362 (1981).

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