tRNA synthetases, metRS

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for...

Reexamination Certificate

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C435S252300, C435S320100, C435S325000, C435S069700, C536S023200, C536S023700, C536S023400, C530S387900

Reexamination Certificate

active

07087417

ABSTRACT:
The invention relates to metRS polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques. Also disclosed are methods for utilizing metRS polypeptides and polynucleotides in diagnostic assays.

REFERENCES:
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patent: 2003/0109690 (2003-06-01), Ruben et al.
GenBank Accession No. P56192 (Nov. 1997).
GenBank Accession No. CAB11680 (Sep. 1997).
Mirande M, Aminoacyl-tRNA synthetase family fron prokaryotes and eukaryotes: structural domains and their implications. Prog. Nucleic Acid Res. Mol. Biol. (1991) 40:95-142.
Kisselev et al. Aminoacyl-tRNA synthetases from higher eukaryotes. Prog. Nucleic Acid Res. Mol. Biol. (1994) 48:83-142.
Lage et al. Cloning of a human cDNA encoding a protein with high homology to yeast methionyl-tRNA synthetase. Gene (Oct. 1996) 178:187-189.
GenBank Accession No. SYBYMT (May 1985).
GenBank Accession No. Z98978, (Sep. 28, 1997).
NCI-CGAP, GenBank Accession No. AA280602 (Apr. 2, 1997).
Lage, et al., GenBank Accession No. P56192 (Oct. 1, 1997).
Murphy et al., GenBank Accession No. CAB11680 (Sep. 8, 1997).
Wood et al., GenBank Accession No. CAB51763 (Jul. 30, 1999).
Kisselev et al., “Aminoacyl-tRNA Synthetases from Higher Eukaryotes”,Progress in Nucleic Acid Research and Molecular Biology, vol. 45, pp. 83-142 (1994).
Mirande et al., “Aminoacyl-tRNA Synthetase Family from Prokaryotes and Eukaryotes: Structural Domains and Their Implications”,Progress in Nucleic Acid Research and Molecular Biology, vol. 40, pp. 95-142 (1991).
Lage et al., “Cloning of a Human cDNA Encoding a Protein with High Homology to Yeast Methionyl-tRNA Synthetase”,Gene, vol. 178, pp. 187-189 (1996).

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