Trk neurotrophin binding motifs

Details Trk neurotrophin binding motifs Trk neurotrophin binding motifs

1995-05-03

1997-11-18

Adams, Donald E.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

25 or more amino acid residues in defined sequence

536 231, 536 235, C07K 1471, C07H 2100

Patent

active

056889119

ABSTRACT:
Trk neurotrophin binding motifs consisting of 24 amino acid, leucine rich domains are described as well as nucleic acid sequences encoding such peptides. The leucine rich motifs are useful in screens for novel agonists and antagonists of the neurotrophins.

REFERENCES:
Urfer et al., EMBO J., vol. 14, pp. 2795-2805, 1995.

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