Triterpenic saponin having pharmacological potency

Details Triterpenic saponin having pharmacological potency Triterpenic saponin having pharmacological potency

1980-05-12

1982-06-15

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated via claimed linking group, bond, chelating agent,...

536 5, 536 181, A61K 3170, C07H 1520

Patent

active

043351131

ABSTRACT:
The present invention concerns a new triterpenic saponin derived from caulophyllogenin, the process for extracting it from varieties of Chrysanthellum, and its therapeutic use.
This saponin is characterized as being the ester of O-.beta.-D-glucosyl-3.beta.-caulophyllogenin and an oligosaccharide comprising two units of L-rhamnose and two units of D-xylose. It is extracted from vegetable matter and purified using pressurized liquid preparative chromatographic techniques.
This saponin is useful in human and veterinary therapeutics in phlebology, rheumatology, and traumatology.

REFERENCES:
patent: 3163636 (1964-12-01), Wagner et al.
patent: 3238190 (1966-03-01), Erbring et al.
patent: 3713980 (1973-01-01), Balsam et al.
patent: 3723410 (1973-03-01), Persinos
patent: 4148928 (1979-04-01), Sodini et al.
patent: 4171430 (1979-10-01), Matsushita et al.
Strigina et al., "Chem. Abst.", vol. 82, 1975, 125,562j).

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