Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-08-15
2011-11-08
Saeed, Kamal (Department: 1626)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C548S197000, C514S370000, C514S371000
Reexamination Certificate
active
08053581
ABSTRACT:
The present invention relates to 2,4,5-trisubstituted thiazole compounds of formula (I) or all possible isomers, prodrugs, pharmaceutically acceptable salts, solvates or hydrates thereof for the inhibition of plasma PLTP activity and/or plasma CETP activity, wherein the substituents are as defined in the specification; a process for the preparation of the compounds of formula (I); a pharmaceutical composition comprising the compound of formula (I) and its use for the preparation of a medicament for treatment and/or prevention of diseases associated with the increased plasma PLTP activity and/or the increased plasma CETP activity in a mammal, such as atherosclerosis, cardiovascular diseases and peripheral vascular diseases, etc.
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Guo Changbin
Jiang Xiancheng
Li Song
Wu Zhong
Xiao Junhai
Brinks Hofer Gilson & Lione
Grazier Nyeemah A
Institute of Pharmacology and Toxicology Academy of Military Med
Saeed Kamal
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