Trisubstituted naphthylalkylamides for disorders of the melatoni

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

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514595, 514599, 514617, 564 26, 564 47, 564 74, 564189, 564190, 564192, 564209, A61K 3116, A61K 3117, C07C33506, C07C27506

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055917755

ABSTRACT:
The invention relates to a compound selected from those of formula (I): ##STR1## in which R, R.sub.1, R.sub.2 and R.sub.3 are as defined herein for use in the treatment of a disorder of the melatoninergic system.

REFERENCES:
Yous et al., J. Med. Chem. 35(8), pp. 1484-1486 (1992).
CAS Abstract of published German Patent Application DE3828566, 1990.
Derwent Abstract of published German Patent Application DE3828566, 1990.
J. Med. Chem. 35, pp. 1484-1486 (1992).
Moritoki H. et al., Eur. J. Pharmacol. 35, pp. 185-198 (1976).
Morgan P. Journal of Neuroendocrinology 1, pp. 1-4 (1989).

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