Tris(isonitrile)copper(I) adducts for preparing radionuclide com

Compositions – Miscellaneous

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556 7, 556 13, 556110, 558302, 534 14, 424 11, C07F 1300, C07F 108, C07C11902

Patent

active

048851000

ABSTRACT:
Tris(isonitrile)copper(I) complex salts with anions selected from BF.sub.4, PF.sub.6, ClO.sub.4, I, Br, Cl and CF.sub.3 COO are useful in preparing radionuclide complexes rapidly at room temperature. Preferred isonitrile ligands are ether isonitriles. The tris(isonitrile)copper(I) adducts enable technetium complexes, such as those of Tc99m, to be prepared easily just prior to their use as imaging agents.

REFERENCES:
patent: 3117938 (1964-01-01), Byrrus
patent: 3197493 (1965-07-01), Allison
patent: 4451665 (1984-05-01), Nugent

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