Triptolide prodrugs having high aqueous solubility

Details Triptolide prodrugs having high aqueous solubility Triptolide prodrugs having high aqueous solubility

1999-09-02

2000-11-21

Owens, Amelia A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549218, 549297, 549543, 544148, 536 111, 536 41, C07D30777

Patent

active

061505390

ABSTRACT:
Compounds useful in immunosuppressive and anti-inflammatory treatment are described. The compounds are hydrolyzable triptolide analogs with improved water solubility and generally lower toxicity than the parent compound.

REFERENCES:
patent: 5972998 (1999-10-01), Jung et al.
Yu, D Q et al "Structure Modification of Triptolide" CA 118: 182770 (1993).

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