Triptolide derivatives useful in the treatment of autoimmune dis

Details Triptolide derivatives useful in the treatment of autoimmune dis Triptolide derivatives useful in the treatment of autoimmune dis

1998-05-12

1999-10-26

Owens, Amelia

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549297, 549298, A61K 3134, C07D40700

Patent

active

059729988

ABSTRACT:
The present invention relates to novel triptolide derivatives and a method of treating a patient suffering from an autoimmune disease comprising administering to a patient an effective amount of the novel triptolide derivatives.

REFERENCES:
patent: 5580562 (1996-12-01), Lipsky et al.
patent: 5663335 (1997-09-01), Qi et al.
Chemical Abstracts, vol. 118, No. 19, May 10, 1993, Abstract No. 18277m, D.Q. Yu et al, "Structure modification of triptolide", p. 21, XP002073427, compound with CN(RN):141069-12-7, see abstract & Yaoxue Xuebao, vol. 27, No. 11, 1992, pp. 830-836.
Chemical Abstracts, vol. 119, No. 9, Aug. 30, 1993, Abstract No. 91202g, C.P. Zhang et al, "Diterpenoids from leaves of Tripterygium wildfordij", p. 649, XP002073428, compound with CN(RN):147809-20-9, see abstract & Yaoxue Xuebao, vol. 28, No. 2, 1993, pp. 110-115.
J. Am. Chem. Soc--94:20, pp. 7194-7195, (1972).
J. Am. Chem. Soc. 104, pp. 867-869, (1982).
Kutney, et al., Recl. Trav. Chim. Pays-Bas 115, pp. 77-93 (1996).
Gu Ke-xian, et al., Chinese Pharmacological Bulletin 10(1), pp. 54-57 (1994).
Zhang et al., Acta Pharmaceutica Sinica, vol. 28, No. 2, pp. 110-115 (1993).
Fu-xiao, et al., Acta Botanica Sinica, vol. 34, No. 8, pp. 618-621 (1992).
van Tamelen, et al., J. Am. Chem. Soc. vol. 104, No. 6, pp. 1785-1786 (1982).

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