Triptolide derivatives as immunomodulators and anticancer...

Details Triptolide derivatives as immunomodulators and anticancer... Triptolide derivatives as immunomodulators and anticancer...

2006-03-28

2006-03-28

Saeed, Kamal A. (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C549S300000

Reexamination Certificate

active

07019151

ABSTRACT:
Compounds having the structure I:are useful for inducing cell death (apoptosis) and in immunosuppression. In structure I, R1is H or R, R being selected from lower alkyl, alkenyl, alkynyl, and allenyl, or, R1together with R2=O (oxo); R2=OH, or, R1and R2together=O (oxo); CR3R5and CR4R6are selected from CH2, CHOH and CROH; at least one of R1, R5and R6is R; and at least one of CR3R5and CR4R6is CH2.

REFERENCES:
patent: 5430054 (1995-07-01), Qian et al.
patent: 5663335 (1997-09-01), Qi et al.
patent: 6004999 (1999-12-01), Jung et al.
patent: 6150539 (2000-11-01), Musser
patent: 6620843 (2003-09-01), Fidler et al.
Copy of International Search Report in PCT/US2003/040104, published on Jul. 15, 2004 as WO 2004/058246 A1.

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