Triphenylethylene compounds as selective estrogen receptor...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

Reexamination Certificate

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C514S570000

Reexamination Certificate

active

07442833

ABSTRACT:
Compounds of formula (I):with a variety of therapeutic uses, more particularly novel prodrugs that are particularly useful for delivering a parent compound for selective estrogen receptor modulation.

REFERENCES:
patent: WO-92/04310 (1992-03-01), None
patent: WO-01/77055 (2001-10-01), None
patent: WO-01/77057 (2001-10-01), None
patent: WO-03/016270 (2003-02-01), None
Ross V. Weatherman, Nicola J. Clegg, Thomas S Scanlan Differential SERM activation of the estrogen receptors (ERalpha and ER beta) at AP-1 sites Chemistry and Biology 8 (2001) 427-436.
Ross V. Weatherman, Nicola J. Clegg, Thomas S. Scanlan Differential SERM activation of the estrogen receptors (ERalpha and ERbeta) at AP-1 sites Ross V. Weatherman, Nicola J. Clegg, Thomas S. Scanlan Chemistry and Biology 8 (2001) 427-436.
Scanlan T S et al.; Differential SERM Activation of the Estrogen Receptors (ERalpha and ERbeta) at AP-1 Sites; Chemistry and Biology, Current Biology; 2001; vol. 8, No. 5; 427-436; London, GB.
Willson T. M. et al.; 3-U4-(1,2-Diphenylbut-1-enyl)phenylacrylic Acid: A Non-Steroidal Estrogen with Functional Selectivity for Bone over Uterus in Rate; Journal of Medicinal Chemistry; May 25, 1994; vol. 37, No. 11; 1550-1552; American Chemical Society; Washington, US.
European Office Action for Application 04809876.8-2117 (Corresponding Application to U.S. Appl. No. 10/575,038).; Apr. 27, 2007.

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