Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase
Patent
1997-03-19
1998-10-13
Wax, Robert A.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Hydrolase
435 691, 4352523, 4352543, 4351723, 4353201, 536 232, C12N 962, C12N 1557, C12N 1511, C12N 1580
Patent
active
058211047
ABSTRACT:
The present invention relates to a tripeptidyl aminopeptidase, a DNA construct encoding the tripeptidyl aminopeptidase, a method of producing tripeptidyl aminopeptidase and methods of reducing the tripeptidyl aminopeptidase production in cells in which tripeptidyl aminopeptidase activity is undesirable.
REFERENCES:
patent: 5616485 (1997-04-01), Hadary et al.
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Lees, et al., Chemical Abstract, vol. 113, No. 15, Abstract 128464 (Oct. 8, 1990).
Tsyperovych, et al., Ukrainian Biochemical Journal System of Aminopeptidases from Aspergillus flavus, vol. 49 No. 1, pp. 101-105, (1977).
Krieger, et al., FEBS Letters vol. 352, pp. 385-388 (1994).
Balow, et al., Biological Chemistry, vol. 258, No. 19, pp. 11622-11628 (Oct. 10, 1983).
McDermott et al., Biochemical Society Transactions, vol. 18, p. 667, (1990).
Watanabe, Y., et al., Biochemistry International, vol. 27, "Acidic tripeptidyl aminopeptidase in rat liver tritosomes: partial purification and determination of its primary substrate specificity", pp. 869-877, 1992 .
Halkier Torben
Holm Kaj Andre
Lehmbeck Jan
Rasmussen Grethe
Lambiris Elias J.
Moore William W.
Novo Nordisk A S
Wax Robert A.
Zelson Steve T.
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