Tripeptides having an antidepressive and prolactin-releasing act

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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424177, C07C10352, A61K 3700

Patent

active

039311392

ABSTRACT:
The invention relates to tripeptide amides containing pyroglutamine, proline and histidine as amino acids having anti-depressive activity and a process for their manufacture.

REFERENCES:
patent: 3725380 (1973-04-01), Konig et al.
patent: 3795666 (1974-05-01), Konig et al.
Inouye et al.: Bull. Chem. Soc. Japan, 44, 1689-1691, (1971).
Rivier et al.: J. Med. Chem., 15, 479-482, (1972).
Chang et al.: J. Med. Chem., 14, 481-483, (1971).
Bowers et al.: Biochem. Biophys. Res. Comm., 40, 683-691, (1970).
Chang et al.: J. Med. Chem., 14, 484-487, (1971).

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