Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1987-05-04
1989-03-14
Phillips, Delbert R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 19, 548569, 548342, 548215, 548950, 544400, 544159, 544168, 546247, 546335, 546336, 530331, A61K 3443, C07K 506, C07K 508, C07D24104, C07D26530, C07D21130, C07D21170, C07D26302, C07D23354, C07D20704
Patent
active
048124427
ABSTRACT:
Enzyme tripeptides of the formula: ##STR1## and analogs thereof which inhibit renin and are useful for treating various forms of renin-associated hypertension, hyperaldosteronism and congestive heart failure; compositions containing these renin-inhibitory peptides, optionally with other antihypertensive agents; and methods of treating hypertension, hyperaldosteronism or congestive heart failure or of establishing renin as a causative factor in these problems employing the novel tripeptides.
REFERENCES:
patent: 4638047 (1987-01-01), Szelke et al.
Bock Mark G.
Boger Joshua S.
Evans Ben E.
Chow Frank S.
Merck & Co. , Inc.
Pfeiffer Hesna J.
Phillips Delbert R.
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