Triiodized N-methyldicarboxylic acid anilides

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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2602393R, 26029377, 2602472A, 26032685, 2604045, 260516, 260519, 260544N, 260558P, C07C10150

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active

040012980

ABSTRACT:
Triiodized N-methyldicarboxylic acid anilides of the Formula ##STR1## wherein R.sub.1 is hydrogen, halogen, carboxyl, N-monoacylamino, N-monoalkoxyacylamino, N-alkyl-N-acylamino, N-alkyl-N-alkoxyacylamino, N,N-diacylamino, N-acylaminomethyl, ##STR2## wherein A is alkylene of 2 or 3 carbon atoms which can be interrupted by an oxygen atom, and R.sub.3 and R.sub.4 are each hydrogen, lower alkyl or hydroxyalkyl, or R.sub.3 and R.sub.4 together with the nitrogen atom form a 5 to 7 member heterocyclic ring which can contain a further oxygen, nitrogen, or sulfur hetero atom; R.sub.2 is halogen, hydroxy, lower alkoxy, hydroxyalkoxy or alkoxyalkoxy; and X is straight or branched alkylene of 2-14 carbon atoms interrupted by one or more oxygen or sulfur atoms, and the salts of these compounds with physiologically compatible bases are valuable radiopaque agents.

REFERENCES:
patent: 3542861 (1970-11-01), Ackerman
patent: 3732293 (1973-05-01), Ackerman

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