Triggered release hydrogel drug delivery system

Details Triggered release hydrogel drug delivery system Triggered release hydrogel drug delivery system

2006-06-27

2006-06-27

Bianco, Patricia (Department: 3761)

Surgery

Means for introducing or removing material from body for...

Treating material introduced into or removed from body...

C604S096010, C604S103010, C604S103060, C604S265000, C604S509000, C427S002240, C427S002250

Reexamination Certificate

active

07066904

ABSTRACT:
The invention features a method for triggering release of a drug from a hydrogel polymer to tissue at a desired location of the body using a catheter. A portion of the catheter is coated on its outer surface with a polymer having the capacity to incorporate a predetermined substantial amount of drug which is immobilized in the polymer until released by a triggering agent or condition that is different from physiological conditions. Upon contact with a triggering agent or condition, the polymer reacts, e.g., swells or contracts, such that the drug is delivered to the desired body tissue. A balloon catheter is shown in which the hydrogel is carried on the exterior surface of the balloon.

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