Trifluoromethylimidazoles and a method for their preparation

Details Trifluoromethylimidazoles and a method for their preparation Trifluoromethylimidazoles and a method for their preparation

1977-02-02

1978-11-14

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

2603068R, 548336, 548341, 544405, 544235, 544370, 546210, 546278, C07D23112, C07D40104

Patent

active

041255305

ABSTRACT:
4(5)-Trifluoromethylimidazoles having optional substituents in the 1 and 2 positions are provided. The novel 4(5)-trifluoromethylimidazoles are prepared by reacting a 1,1-dihalo-3,3,3-trifluoroacetone compound with an appropriate carboxaldehyde and ammonia. The 4(5)-trifluoromethylimidazoles are useful as anti-gout and anti-hyperuricemic agents.

REFERENCES:
patent: 3652579 (1972-03-01), Hofber et al.
patent: 3691178 (1972-09-01), Baldwin et al.
patent: 3786061 (1974-01-01), Novello et al.
patent: 3818014 (1974-06-01), Baldwin et al.

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