Trifluoromethylbenzylphosphonates useful in treating osteoporosi

Details Trifluoromethylbenzylphosphonates useful in treating osteoporosi Trifluoromethylbenzylphosphonates useful in treating osteoporosi

1991-07-18

1994-04-05

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

544 57, 544157, 544337, 546 22, 546 23, C07F 902, C07F 928, C07D27912, C07D26530

Patent

active

053006879

ABSTRACT:
Novel benzylphosphonate compounds of the general formula I: ##STR1## are disclosed as useful in treating bone wasting diseases including postmenopausal osteoporosis in increasing in mammals bone formation and bone mass.

REFERENCES:
Hermant et al., J. Am. Chem. Soc. (1990) 112 1214-1221.
Terada et al., Chemical Abstracts (1990) 112 235,189p.
Brinkwerth, Chemical Abstracts (1986) 104 35,465y.

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