Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1992-07-24
1995-07-04
Ivy, C. Warren
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
546147, 546164, 546233, 548567, 548568, C07D21106, C07D20704
Patent
active
054301513
ABSTRACT:
The present invention relates to new trifluoromethyl-containing pseudopeptides of the general formula (I) ##STR1## in which W, A, B, D, E, R.sub.1, R.sub.2 and R.sub.3 have the meaning as outlined of their making and use as pharmaceuticals.
REFERENCES:
patent: 3855228 (1974-12-01), Bailey
patent: 3927000 (1975-12-01), Bailey
patent: 3956333 (1976-05-01), Bailey
Methods in Enzymology, vol. XXXIV, "Affinity Techniques, Enzyme Purification: Part B", Bovine Trypsin and Thrombin, Hixson, Jr. and A. H. Nishikawa, pp. 440-448, Academic Press; 1974.
Methods in Enzymology, vol. XXXIV, "Affinity Techniques, Enzyme Purification: Part B", Chymotrypsin(s), Tomlinson, et al., pp. 415-420, Academic Press 1974.
Affinity Chromatography, Biospecific Sorption; "Affinity Chromatography of Chymotrypsin on Soybean Trypsin Inhibitor Sepharose: Applications In Genetics And Nuclide Labelling", Gabel, Kasche, Amneus and Lundqvist, pp. 99-102, Pergamon Press, 1977.
Applied Microbiology and Biotechnology, Springer-Verlag 1979, Biotechnol. 6.; p. 195-(1979); "Recovery of Free Enzymes from Product Liquors by Bio-Affinity Adsorption: Trypsin Binding by Immobilised Soybean Inhibitor", Halling and Dunnill.
The Journal of Biological Chemistry, vol. 225, No. 15, Aug. 10, 1980, p. 7089, "Human Red Cell Purine Nucleoside Phosphorylase, Purification By Biospecific Affinity Chromatography and Physical Properties", Osborne, Mar. 17, 1980.
Hoppe-Seyler's Z. Physiol. Chem., vol. 361, p. 543, Apr. 1980, "Purification of Human and Bovine Alkaline Phosphatases by Affinity Chromatograph", Mossner, Boll and Pfleiderer.
Analytical Biochemistry, vol. 107, p. 341, (1980), "Affinity Chromatographic Sorting of Carboxypeptidase A and its Chemically Modified Derivatives", Cueni, Bazzone, Riordan & Vallee, Mar. 31, 1980.
Hoppe-Seyler's Z. Physiol. Chem., vol. 359, p. 1019, Aug. 1978, "Affinity Chromatograph of Bovine Bran .beta.-Hexosaminidases with Substrate As Affinity ligand"., Lisman and Overdijk, May 1978.
Biochem. J. (1978), vol. 175, p. 125, "Purification of the Hexokinases by Affinity Chromatography on Sepharose-N-Aminoacylglucosamine Derivatives", Wright, Warsy, Holroyde and Trayer, Feb. 1978.
Archives of Biochemistry and Biophysics, vol. 198, No. 2, Dec., 1979, p. 533, "Quantitative Affinity Chromatograph of .alpha.-Chymotrypsin", Dunn and Gilbert, Aug. 10, 1979.
Understanding Enzymes, Third Ed. (Horwood Press, 1991), pp. 309-310, Trevor Palmer.
P. Brongham et al., Synthesis (1987), 1015.
W. Adam et al., J. Org. Chem. 52, 2800 (1987).
R. Curci et al., J. Org. Chem 53, 3890 (1988).
J. Med. Chem. 34, 1225 (1991).
J. R. Luly et al., J. Org. Chem 52, (1987), 1487.
J. Org. Chem. 27, 1406 (1962).
J. Med. Chem. 32, 1371 (1989).
Hansen, J. Billich, S., Schylze, T., Sukrow, S. and Molling, K. (1988), EMBO Journal, vol. 7, No. 6, pp. 1785-1791.
Journal of Virological Methods 20, 1988, 309-321.
H. Buhlmayer et al., J. Med. Chem. 31, 1839 (1988).
G. J. Hansen et al., J. Org. Chem. 50, 5399 (1985).
Habich Dieter
Hansen Jutta
Paessens Arnold
Roben Wolfgang
Bayer Aktiengesellschaft
Davis Zinna N.
Ivy C. Warren
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