Trifluoromethyl analogs of X-ray contrast media for magnetic res

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent

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514492, 514500, 514501, 514502, 436173, 1286534, 556 45, 556 51, 556 50, 556 61, 556 69, 556 81, 556106, 556110, 556111, 556118, 556119, 556132, 556138, 556139, 556147, A61B 5055

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053857240

ABSTRACT:
Methods and compositions are disclosed for enhancing .sup.19 F magnetic resonance imaging which utilize trifluoromethyl derivatives of iodinated X-ray contrast media. Typical magnetic resonance contrast media within the scope of the present invention include bis(trifluoromethyl)benzene derivatives, tris(trifluoromethyl)benzene derivatives, tetrakis(trifluoromethyl)benzene derivatives, and other related trifluoromethylated benzene derivatives.

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Ghuari, FYK, Methodol. Surv. Biochem. Anal. 20:321-324 (1990).
Ghuari, FYK, J. Pharmaceutical & Chemical Analysis 8(8-12):939-944 (1990).

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