Trifluorinated-1.alpha.,25S-dihydroxy vitamin D3 compounds

Details Trifluorinated-1.alpha.,25S-dihydroxy vitamin D3 compounds Trifluorinated-1.alpha.,25S-dihydroxy vitamin D3 compounds

1989-11-16

1991-08-13

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

9,10-seco- cyclopentanohydrophenanthrene ring system doai

552653, A01N 4500, C07J17200

Patent

active

050396714

ABSTRACT:
26, 26, 26-Trifluoro-1.alpha., 25-dihydroxy-cholecalciferol, and the 25R or 25S epimer thereof, are described, as well as processes and intermediates utilized to prepare the same, as well as pharmaceutical compositions containing the same. 26,26,26-trifluoro 1.alpha., 25-dihydroxycholecalciferol and the 25R or 25S epimer thereof are useful agents in the treatment of disease states such as osteoporosis, oseodystrophy and leukemia.

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