Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1993-05-06
1995-01-31
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
514286, 514293, 424 9, 530386, 5303871, 540465, 540472, A61K 3144, A61K 31675, C07D47118, C07D47122
Patent
active
053858930
ABSTRACT:
Tri- and tetra-cyclopolyazamacrocyclophosphonic acid compounds and their derivatives are disclosed which may form inert complexes with Gd, Mn or Fe ions. The overall charge of the complex can be varied to alter the in vivo biolocalization. The complexes are useful as contrast agents for diagnostic purposes.
REFERENCES:
patent: 2609390 (1950-06-01), Bernsworth
patent: 3331773 (1967-07-01), Gunderson
patent: 3336221 (1967-07-01), Ralston
patent: 3434969 (1969-03-01), Ralston
patent: 4880008 (1989-11-01), Lauffer
patent: 4899755 (1990-02-01), Lauffer
patent: 4980148 (1990-12-01), Dean
J. Org. Chem., 53, 3521-3529 (1988), Bottino et al.
J. Nucl Med., 25, 506-513 (1984), Koutcher et al.
C. J. Broan et al., J. Chem. Soc., Chem. Commun., 1739-1741 (1990).
C. J. Broan et al., J. Chem. Soc., Chem Commun., 1738-1739 (1990).
I. K. Adzamli et al., J. Med Chem., 32, 139, 144 (1989).
J. Magnetic Resonance, 33, 83-106 (1979), Brunner et al.
Magnetic Resonance Annual, 231-266 Raven Press, N.Y. (1985), Wolf et al.
Frontiers of Biol. Energetics l, 752-759 (1978), Lauterbur et al.
Datlow P. I.
Kimble Karen L.
Shah Mukund J.
The Dow Chemical Company
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