Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Silicon containing doai
Patent
1985-11-20
1990-01-16
Bond, Robert T.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Silicon containing doai
514291, 514411, 540452, 540456, 435898, 435886, 435118, A61K 31395, A61K 31695, C07D49816, C07F 704
Patent
active
048943665
ABSTRACT:
This invention relates to tricyclo compounds useful for treatment and prevention of resistance by transplantation, graft-versus-host diseases by medulla ossium transplantation, autoimmune diseases, infectious diseases, and the like, which can be represented by the following formula: ##STR1## to a process for their production, to a pharmaceutical composition containing the same and to a use thereof.
REFERENCES:
patent: 3244592 (1966-04-01), Arai
patent: 4212881 (1980-07-01), Sasaki et al.
J. A. Findlay: Canadian Journal of Chemistry, vol. 58 (1980), pp. 579-590.
Arai et al., Journal of Antibiotics, vol. 15, (1962), pp. 231-232.
Korzybski, "Antibiotics-Origin, Nature and Properties", vol. II, 1978.
Chemical Abstracts, vol. 90, No. 3, 1979, p. 635, Abstract No. 22856u.
Chemical Abstracts, vol. 97, No. 21, 1982, p. 793, Col. 1, Abstract No. 182063f.
Goto Toshio
Hatanaka Hiroshi
Kino Tohru
Okuhara Masakuni
Tanaka Hirokazu
Bond Robert T.
Fujisawa Pharmaceutical Company, Ltd.
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