Tricyclic thienothiopyrans as pharmaceutical intermediates

Details Tricyclic thienothiopyrans as pharmaceutical intermediates Tricyclic thienothiopyrans as pharmaceutical intermediates

1991-10-15

1992-12-29

Brust, Joseph Paul

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

546 80, 548431, 548430, C07D49518

Patent

active

051752840

ABSTRACT:
Intermediates are described for preparing conformationally constrained tricyclic thienothiopyran compounds that are topically effective carbonic anhydrase inhibitors useful in the treatment of ocular hypertension and glaucoma associated therewith.

REFERENCES:
patent: 4174396 (1979-11-01), Jarque et al.
patent: 4619939 (1986-10-01), Maren
patent: 4677115 (1987-06-01), Baldwin et al.
patent: 4797413 (1989-01-01), Baldwin et al.
patent: 5011942 (1991-04-01), Blacklock et al.

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