Tricyclic substituted hexahydrobenz [e]isoindole alpha-1 adrener

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514252, 514267, 544145, 544163, 544234, 544249, 544250, 544251, 544278, 544350, 544409, 546114, 546115, 546118, 546286, 548427, 549 57, 549236, A61K 31505, C07D49504, C07D49514, C07D48704

Patent

active

055978231

ABSTRACT:
The present invention relates to a compound of the formula ##STR1## and the pharmaceutically acceptable salts thereof wherein W is a tricyclic heterocyclic ring system; which is an .alpha.-1 adrenergic antagonist and is useful in the treatment of BPH; also disclosed are .alpha.-1 antagonist compositions and a method for antagonizing .alpha.-1 receptors and treating BPH.

REFERENCES:
patent: 5049564 (1991-09-01), DeBernardis et al.

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