Tricyclic steroid analogs

Details Tricyclic steroid analogs Tricyclic steroid analogs

1993-01-14

1994-03-08

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Cyclopentanohydrophenanthrene ring system containing

552502, 560117, 560256, 562499, C07C 6974, C07C 6702

Patent

active

052929060

ABSTRACT:
Novel tricyclic steroid analogs are disclosed which are 1H-benz[e]indene dodecahydro compounds that are useful for enhancing GABA-induced chloride currents at the GABA receptor/chloride ionophore complex and can be represented by the following structural formulas: ##STR1## wherein R.sub.1 =H or C.sub.1 -C.sub.4 alkyl or fluoroalkyl;

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Majewska, Biochm. Pharmacal. 36, 3781-3788 (1987).
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