Tricyclic pteridinones and a process for their preparation

Details Tricyclic pteridinones and a process for their preparation Tricyclic pteridinones and a process for their preparation

1998-12-18

2000-02-15

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

544115, 544251, 544322, C07D41700

Patent

active

060254890

ABSTRACT:
This invention is directed to tricyclic pteridinones of formula (I): ##STR1## where R, R.sup.1, A, B and D are described herein. These compounds and their pharmaceutically acceptable salts are disclosed as being combined inotropic and vasodilator agents.

REFERENCES:
patent: 4229452 (1980-10-01), Warner, Jr. et al.
patent: 4440929 (1984-04-01), Lee et al.
patent: 4446323 (1984-05-01), Freed et al.
patent: 4696928 (1987-09-01), Ellames et al.
patent: 4904658 (1990-02-01), Tseng et al.
patent: 5602252 (1997-02-01), Davey
Brown, D. J. et al., Triazolopteridines II* Simple s-Triazolo[3,4-h]pteridines and Some [5,1-h] and [4,3-a] Isomers, Aust. J. Chem. (1981) 34:2635-9.
Parthasarathy, P.C. et al., Heterocyclic N-Oxides: Part II-Syntheses of New Ring Systems N-Oxides of Dihydromidazo & Pyrimido [2,1-h]pteridines & Azadihydroimidazo & Pyrimido[1,2-a]quinoxalines & Their Antiprotozoal Activities, Indian Journal of Chemistry, (1983) 22B:1233-1235.
Gakhar, H.K. et al., Substituted Benzimidazo[2,1-h]pteridine-2,4-diones, Monatshefte fur Chemie (1984) 115:757-763.
Oguchi, et. al., "Syntheses of Quinoxaline . . . ", Chem. Abs., vol. 96 (1982), Abs.# 162646z, pp. 751-752.
Sakamoto et. al., "Preparation of Imidazoquinoxalinones . . . ", Chem. Abs., vol. 120 (1994), Abs.# 217730u, pp. 1088-1089.

Affiliated with

Also associated with

Rating

Tricyclic pteridinones and a process for their preparation does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Tricyclic pteridinones and a process for their preparation, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tricyclic pteridinones and a process for their preparation will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1907051