Tricyclic pteridinones and a process for their preparation

Details Tricyclic pteridinones and a process for their preparation Tricyclic pteridinones and a process for their preparation

1994-02-08

1997-02-11

Bernhardt, Emily

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

544 60, 544251, 544322, C07D48714, A61K 31505

Patent

active

056022522

ABSTRACT:
This invention relates to novel tricyclic pteridinones, their aza analogs and their pharmaceutically acceptable salts. Further encompassed by the invention is a novel process for the production of the tricyclic pteridinones and their aza analogs. The compounds of the invention exhibit cardiovascular properties, particularly mixed vasodilation and selective venous and arterial dilation. Pharmaceutical compositions are proposed for the compounds.

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Sakamoto et al, Chemical Abstracts, vol. 120, No. 217730 (1994) (Abstract for WO 93 20,077 Oct. 14, 1993).

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