Tricyclic prostaglandin intermediates

Details Tricyclic prostaglandin intermediates Tricyclic prostaglandin intermediates

1976-07-26

1977-10-11

Love, Ethel G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

560 55, 560 51, 560255, 560 56, 260333, 260338, 2603409P, 2603452, 26034522, 2604105, 2604482R, 2604488R, 260514D, 560 53, 560 82, 260520B, 260599, 260617F, 260618R, C07D31904

Patent

active

040534855

ABSTRACT:
Process for preparing bicyclic diols of the formula ##STR1## wherein C.sub.p H.sub.2p is a valence bond or alkylene of one to 4 carbon atoms, inclusive, with one or 2 carbon atoms in the chain between the phenylene ring and --O--; wherein Y is a hydrocarbyl or substituted hydrocarbly group; and wherein indicates attachment to the cyclopropane ring in exo or endo configuration. These diols and the intermediates prepared herein are useful intermediates in preparing prostaglandin analogs having pharmacological utility.

REFERENCES:
patent: 3873570 (1975-03-01), Kelly
patent: 3873571 (1975-03-01), Kelly

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