Tricyclic lactams active as antihypertensive agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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540521, 540522, 540523, C07D51304, A61K 3155

Patent

active

049735853

ABSTRACT:
This invention relates to derivatives of fused bicyclic or tricyclic lactams, to the intermediates and processes useful for their preparation and to their pharmacological effect in inhibiting the angiotensin converting enzyme and to their end-use application in the treatment of hypertension.

REFERENCES:
patent: 4584294 (1986-04-01), Ruyle
P. R. Andrews et al., "Conformational Analysis and Active Site Moddeling of Angiotensin-Converting Enzyme Inhibitors", J. Med. Chem., 28, 393-399, 1985.

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