Tricyclic indole derivatives

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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Details

26032629, 2603265SA, 2603265B, C07D491056, C07D49504

Patent

active

043093485

ABSTRACT:
Indole derivatives characterized by having a 1,3,4,9-tetrahydropyrano[3,4-b]indole or 1,3,4,9-tetrahydrothiopyrano[3,4-b]indole nucleus with a hydroxyalkanamine or lower alkoxyalkanamine substituent and a lower alkyl group at position 1 are disclosed. The nucelus is optionally further substituted at position 9 and on the aromatic ring. The derivatives are useful diuretic agents, and methods for their preparation and use are also disclosed.

REFERENCES:
patent: 3843681 (1974-10-01), Demerson et al.
patent: 3880853 (1975-04-01), Demerson et al.

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