Tricyclic indole-2-carboxylic acid derivatives

Details Tricyclic indole-2-carboxylic acid derivatives Tricyclic indole-2-carboxylic acid derivatives

1994-11-14

1996-03-05

Haley, Jacqueline

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548436, A61K 3140, C07D20962

Patent

active

054968437

ABSTRACT:
A tricyclic indole-2-carboxylic acid derivative represented by the formula 1: ##STR1## wherein X represents alkyl, halogen or cyano;

REFERENCES:
Gray et al., J. Med. Chem., 34, 1283-1292 (1991).
Salituro et al., Bioorganic & Medicinal Chemistry Letters, 1, (9), 455-460 (1991).
Salituro et al., J. Med. Chem., 33, 2944-2946 (1990).
Salituro et al., J. Med. Chem., 35, 1791-1799 (1992).
Uhle et al., J. Am. Chem. Soc., 77, 3334-3337 (1955).
Huettner, Science, 243, 1611-1613 (1989).
Leeson et al., J. Med. Chem., 36, 1954-1968 (1992).

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