Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1994-06-13
1996-05-14
Datlow, Philip I.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
540561, 540558, 540562, 540563, 544344, C07D48704, A61K 3155
Patent
active
055167748
ABSTRACT:
Tricyclic diazepines of the formula: ##STR1## wherein A, B, D, E, F, Y and Z are defined in the specification which compounds have vasopressin and oxytocin antagonist activity.
REFERENCES:
patent: 3860600 (1975-01-01), Carabateas
Cecil Textbook of Medicine, 19th ed. (1992), Wyngaarden, M.D. editor, pp. 2075-2078.
Yamamura, Y. et al, "OPC-21268, An Orally Effective, Nonpeptide Vasopressin V1 Receptor Antagonist", Science, 252:572-574 (1991).
Yamamura, Y. et al., "Characterization of a novel aquaretic agent, OPC-31260, as an orally effective, nonpeptide V2 antagonist", Br. J. Pharmacol., 105:787-791 (1992).
Albright Jay D.
Delos Santos Efren G.
Reich Marvin F.
Sum Fuk-Wah
American Cyanamid Company
Datlow Philip I.
Eck Steven R.
LandOfFree
Tricyclic diazepine vasopressin antagonists and oxytocin antagon does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Tricyclic diazepine vasopressin antagonists and oxytocin antagon, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tricyclic diazepine vasopressin antagonists and oxytocin antagon will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1895859