Tricyclic derivatives of substituted pyrimidines

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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544250, A61K 3142, C07D23980

Patent

active

047043920

ABSTRACT:
Compounds useful as antiviral agents are depicted in the formula: ##STR1## wherein: X is oxygen or NH, Y is hydrogen, iodo, fluoro, methyl or trifluoromethyl, Z is hydrogen or fluoro and Z' is fluoro; and the wavy line indicates that the group may be above or below the plane of the ring; and the pharmaceutically acceptable acid addition salts thereof.

REFERENCES:
patent: 3709874 (1973-01-01), Moffatt et al.
patent: 4177348 (1979-12-01), Shealy et al.
Journal of Heterocyclic Chemistry, vol. 13, pp. 1015-1020.

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