Tricyclic compounds useful for inhibition of G-protein function

Details Tricyclic compounds useful for inhibition of G-protein function Tricyclic compounds useful for inhibition of G-protein function

1997-09-11

1999-09-28

Peselev, Elli

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 23, 514253, 514256, 514275, 514284, 514290, 536 187, 536 221, 544238, 544361, 544405, 546 93, A61K 3170, A61K 3144, C07M 1500, C07D22116

Patent

active

059588900

ABSTRACT:
Compounds the formula ##STR1## their use as farnesyl transferase protein inhibitors and pharmaceutical compositions containing them are disclosed, especially compounds of the formula ##STR2## wherein R.sup.1, R.sup.2 and R.sup.3 are halo, A and B are each H.sub.2, and R is as defined in the specification.

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