Tricyclic compounds useful for inhibition of G-protein function

Details Tricyclic compounds useful for inhibition of G-protein function Tricyclic compounds useful for inhibition of G-protein function

1996-09-13

1998-09-01

Grumbling, Matthew V.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514255, 514318, 514325, 514320, 514324, 546195, 546196, 546198, 546202, 546256, 546262, 546263, 546265, 544361, 544375, 544386, 544389, 544390, 544399, 544401, A61K 31495, A61K 31505, C07D40314, C07D40114

Patent

active

058011757

ABSTRACT:
Novel compounds of Formula ##STR1## are disclosed. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering a compound of the above formula to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammal such as a human being.

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