Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system
Patent
1997-03-06
2000-03-07
Kight, John
Organic compounds -- part of the class 532-570 series
Organic compounds
Four or more ring nitrogens in the bicyclo ring system
544153, 549387, 549458, 564189, C07D41300, C07D49300, C07D30792, C07C23300
Patent
active
060342390
ABSTRACT:
A compound of the formula: ##STR1## wherein R.sup.1 is an optionally substituted hydrocarbon, amino or heterocyclic group; R.sup.2 is H or an optionally substituted hydrocarbon group; R.sup.3 is H or an optionally substituted hydrocarbon or heterocyclic group; X is CHR.sup.4, NR.sup.4, O or S in which R.sup.4 is H or an optionally substituted hydrocarbon group; Y is C, CH or N; ring A is optionally substituted 5- to 7-membered ring; ring B is an optionally substituted benzene ring; and m is 1 to 4, or a salt thereof, a process for producing it, an intermediate for the production and a pharmaceutical composition comprising it are provided.
REFERENCES:
patent: 5296482 (1994-03-01), Peglion et al.
patent: 5552418 (1996-09-01), Depreux et al.
patent: 5661186 (1997-08-01), Takaki et al.
Macor et al., J. Med. Chem., vol. 35, No. 20 (1992) 3625-32.
Tetrahedron Letters, vol. 36, No. 39 (1995) 7019-7022.
Fukatsu Kohji
Miyamoto Masaomi
Ohkawa Shigenori
Uchikawa Osamu
Covington Raymond
Kight John
Takeda Chemical Industries Ltd.
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