Tricyclic compounds and TXA.sub.2 antagonistic compositions ther

Details Tricyclic compounds and TXA.sub.2 antagonistic compositions ther Tricyclic compounds and TXA.sub.2 antagonistic compositions ther

1989-07-18

1991-04-23

Brust, Joseph Paul

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514309, 514310, 514312, 514313, 514314, 514337, 514338, 514346, 514345, 514347, 514348, 514349, 514350, 514352, 514354, 514355, 514357, 514422, 514423, 514424, 514426, 514427, 514428, 514429, 546141, 546743, 546148, 546149, 546153, 546162, 546269, 546285, 546270, 546274, 548525, 548526, 548527, A61K 3147, A61K 3144, C07D21520, C07D21726

Patent

active

050100874

ABSTRACT:
Novel tricyclic compounds having a TXA.sub.2 -antagonizing activity represented by formula (I): ##STR1## which strongly antagonize an action of thromboxane A.sub.2 and are expected to have preventive and therapeutic effects on ischemica diseases, cerebro-vascular diseases, etc.

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